Popper related news

Toxic Lung Injury in a Patient Addicted to “Legal Highs” – Case Study

Toxic lung injury may manifest itself in many different ways, ranging from respiratory tract irritation and pulmonary edema in severe cases to constrictive bronchiolitis, being a more distant consequence.
It is most often the result of accidental exposure to harmful substances at work, at home, or a consequence of industrial disaster.
This article presents a case of toxic lung injury which occurred after inhalation of legal highs, the so-called “artificial hashish” and at first presented itself radiologically as interstitial pneumonia with pleural effusion and clinically as hypoxemic respiratory insufficiency. After treatment with high doses of steroids, it was histopathologically diagnosed as organizing pneumonia with lipid bodies. . .

Middle-aged man has sudden-onset bilateral central scotomas

A 55-year-old white man presented with the complaint of sudden onset central scotoma in both eyes for 1 month. The patient reported the condition slightly improved from the initial onset.
His medical history was positive for syphilis, HIV, hyperlipidemia and anxiety. The patient reported that he was a former smoker, social drinker and used recreational drugs. His ocular history was unremarkable.
Family ocular history was positive for cataract, glaucoma and age-related macular degeneration. Family medical history was positive for ischemic heart disease, kidney disease and diabetes.. . .

In-Depth Headspage GCMS Analysis of Alkyl Nitrites

Alkyl nitrites are widely abused for recreational purposes, as sexual stimulants, and to improve the physical performance in discotheque dancing. These chemicals are easily available because, with the exception of amyl nitrite, they are not controlled by Italian legislation. Alkyl nitrites are SUbject to photochemical and oxidation reactions. Therefore, the street samples usually contain a high number of chemical components. In the present paper, we report and discuss the synthesis and photochemical degradation of alkyl nitrites, and propose a fast and efficient head space / gas chromatography / mass spectrometry (HS/GC/MS) method for the identification of the degradation products. . .

Severe methemoglobinemia secondary to isobutyl nitrite toxicity: the case of the ‘Gold Rush’

Isobutyl nitrite is one of the popular recreational drugs with high abuse potential that is known to cause methemoglobinemia. While inhaling this recreational drug, often referred to as a ‘popper’, is the typical route of administration, oral ingestion can produce a more rapid and fulminant course of methemoglobinemia. We present the case of a 69-year-old male that presented to our emergency department in extreme, life-threatening methemoglobinemia due to the ingestion of isobutyl nitrite that he obtained from an adult novelty store. . . .

Local doctors back FDA warning against ‘poppers’

GRAND RAPIDS, Mich. (WOOD) — The FDA is warning people to stop using “poppers,” a drug popular in the gay community that can be found online or in stores. They cause muscle relaxation, but the FDA says they can also lead to deadly complications.
They have names like Double Scorpio, Jungle Juice, Extreme Formula and Super RUSH. The product is advertised as tape cleaner for a VHS or nail polish remover.
The bottles says not for consumption, but people who buy them sniff or drink the liquid — which is alkyl nitrites — inside.. . .

Nitrite ‘Poppers’: Here’s Why FDA Warned Against Their Use For Fun, Sex

Nitrite “poppers” are not the same as chicken poppers, pizza poppers, or cheesy corn poppers. While you can still use the latter three for recreation or sexual enhancement, the U.S. Food and Drug Administration (FDA) is warning that you should not use nitrite “poppers” for such purposes. That’s because nitrite “poppers” can lead to all sorts of bad health effects, including death. And death, for most people, is not good for sex.. . .

FDA Warns Nitrate Poppers Cause 'Serious Adverse Health Effects'—What to Know About This Recreational Drug

The Food and Drug Administration (FDA) is urging people not to use nitrite "poppers" for sexual enhancement or recreational use, warning that they can lead to "brain death," along with other health issues.
Poppers come in liquid form in little bottles and are sold online or at adult novelty stores. They're often marketed as nail polish removers or cleaning products (even though they clearly aren't either). They're also packaged in small containers that look like energy shots. . .

FDA reports increased deaths, hospitalizations linked to the sexual stimulant 'poppers'

Washington, DC - Nitrite "poppers" are a class of drugs often used recreationally or for sexual enhancement, though they are usually marketed as nail polish removers or cleaning products.
The FDA recently reported an increase in deaths and hospitalizations linked to the use of poppers and is advising consumers to avoid them.
Poppers are generally sold online or in adult novelty stores in small bottles ranging from 10 to 40 mL. . .

Why Is the FDA Warning About Nitrite Poppers?

The Food and Drug Administration (FDA) is warning consumers not to purchase or use nitrite poppers because they can cause serious health problems, including death, when inhaled or ingested.
Poppers are sold at adult novelty stores or online, and may be marketed as air freshener, vinyl cleaner, or nail polish remover. . .

Deadly sex drug warning

An alarmin rise in South Australians' use of a party and sex-stimulant drug known as "jungle juice" has prompted a warning from experts that it can be deadly.
Amyl nitrite, a liquid that comes in small bottles, gives off fumes that users inhale.
It expands blood vessels, drops blood pressure and accelerates heart rate, causing a "high" that lasts a bout two minutes. . .

High-sight: eyeing unanticipated effects of a ‘harmless’ drug

After a long night of partying, Ivan* found himself staring at his reflection in the mirror. Still somewhat intoxicated he didn’t fully comprehend what he saw, or rather, what he did not see: Where his own face should have been staring back at him, he saw a large black void, a sphere of darkness in the center of his visual field. “There was nothing there, I looked at my face and couldn’t see. . . .

Transient visual loss after amyl Isobutyl nitrite abuse

A 30-year-old man presented a sudden visual decrease following the use of Isobutyl nitrite (popper) while he was at a discotheque. His visual acuity (VA) was 20/50 in the right eye (RE) and 20/63 in the left eye (LE). Ophthalmoscopy revealed symmetric alteration of the foveal reflex with a small yellowish-white spot in the foveal area, much more evident in the RE. Fluorescein angiography and OCT were normal. Visual field showed a mild reduction of central differential light sensitivity. A progressive recovery was noted and at one month's follow-up VA was 20/25 in OU with very faint yellowish-white spots. . . .

Health Canada seizes dozens of illegal products from Edmonton adult store

Health Canada has seized nearly two dozen brands of poppers from an adult store in northwest Edmonton.
Officials from the federal agency took 24 types of products from the Passion Vault on 111 Avenue, said a news release issued on Nov. 25. Authorities seized similar products from stores in Medicine Hat and Toronto. It is unclear if the raids were connected. . . .

20 year old Australian woman paralysed due to nerve damage after inhaling ~360 nitrous oxide canisters a week

A girl in her 20s struggles to walk. She has nerve damage to her spinal cord and may never recover.
The cause? Bingeing on "nangs" — small canisters of nitrous oxide gas designed for whipping cream, but being misused as a recreational drug.
The female student was inhaling 360 nangs a week. Her future is bleak.. . .

New Club Drug: Poppers

The term “poppers” refers to a group of drugs related to the chemical class alkyl nitrite. Its traditional form as a recreational substance is amyl nitrite, although recently a number of other variations have burst onto the scene, such as isobutyl nitrite and isopropyl nitrite.
Since its discovery in 1844, amyl nitrite has been known to be a powerful vasodilator, which means that it increases blood flow by relaxing the smooth muscles that make up blood vessel walls. . .

I Gotta Have My Pops: Artisanal Poppers Are the Next Big Thing in Butt Sex

I was first introduced to poppers (the inhalant that makes anal sex a breeze and dancing a joy) by a lesbian roommate who worked at a nightclub bar, who would return home each night with an armful of confiscated drugs. (It was, suffice it to say, an incredible living arrangement.) One drunken night, when I was 20, she forced me to take my first hit. Seconds later, I found myself rolling around on the carpet, giggling uncontrollably while my face turned red with heat.. . .

Coroner warns of the dangers of party drugs following Darlington man's death

A CORONER has warned of the dangers of recreational drugs after a man was found dead in a Darlington flat after taking poppers. The body of 58-year-old John Martin was discovered by police in the bedroom of his first floor flat in Peel Street, Darlington, after officers were contacted by mental health workers concerned for his welfare. . . .

Woman dies after drinking bottle of poppers usually used as a sex stimulant

A woman has died after drinking an entire bottle of poppers that are commonly used as a sex stimulant. The woman fell ill and died the same day she bought a bottle of XL Gold at Party Time off licence in Arbroath, Angus, a police report has said. . . .

Man who died at Rainbow Serpent drank amyl nitrite 'poppers', sources say

The 22-year-old man that died at the Rainbow Serpent music festival had drunk amyl nitrite, also known as poppers, Hack understands. Authorities said the man was in cardiac arrest before he died on Saturday night, at the five-day trance festival in Lexton, north-west of Ballarat. . . .

Lucille Ball Used Poppers Before Her Death

Comedian and actress Lucille Ball, a gay icon and early ally, was using poppers before to her 1989 death, according to a new forensic report on her death. Reelz’s Autopsy, The Last Hours Of… devotes its Sunday installment into looking at the last days of the star. In a new teaser for the episode, Dr. Michael Hunter said it’s clear Ball used amyl nitrate, a street drug known as poppers, for four years before her death. . . .

Man (33) died after taking 'poppers' during phone sex with theatre director

A YOUNG art director died after taking 'poppers' while having phone sex with prominent theatre director Michael Scott, an inquest heard. Darach Culhane-Nolan (33) was found dead by his mother at his home on the Burrow Road in Sutton, Dublin on March 16 last year. He had been inhaling the chemical amyl nitrate -- more commonly known as 'poppers' -- the night before, while on the phone with Mr Scott. . . .

News anchor dies during sex

A Los Angeles news anchor died in December after overdosing on methamphetamine during a sexual encounter with a male companion at a California hotel, an autopsy report has revealed. Glendale Police were called to a Days Inn hotel around 1.15pm on December 27 to find KTLA news anchor Christopher Burrous unresponsive and suffering from a "medical emergency," officials said in a press release. Police say a male who had been with Burrous at the time placed the call, Fox News reported. . . .

Lucille Ball Was Using Poppers to 'Ease Pains in Her Chest and Heart': Forensic Pathologist

It’s been nearly 30 years since the queen of comedy, Lucille Ball, died, and new discoveries about her life and death are still being uncovered. This Sunday, Reelz’s Autopsy, The Last Hours of … will investigate Ball’s final days, including the popular street drug she used to ease chest pain. “Lucille Ball died of a rupture of the aorta. This tells me how she died, but not what led to such extensive damage to this critical blood vessel,” forensic pathologist Dr. Michael Hunter says in a preview of the series. . . .

Father calls for more talk about risk-taking after son dies from 'huffing' barbecue gas bottle

A Port Lincoln father has sounded out a warning to parents about the potentially fatal consequences of children inhaling from barbecue gas bottles, after the death of his 16-year-old son.
Paddy, 16, died after inhaling gas from an LPG cylinder, an act known as "huffing" while at a friend's house in Port Lincoln on February 9.
"It was just a normal Saturday night and he wound up dead," Adrian told ABC Radio Adelaide.. . . .

Simon Collins, HIV i-Base

Serious vision loss linked to recreational use of poppers has been reported as a case study in this weeks issue of the Lancet. The vision changes have not resolved after six months.
Anna M Gruener and colleagues from Guy’s and St Thomas’ NHS Foundation Trust and Queen Mary’s Hospital, Sidcup published a case of maculopathy associated with use of poppers in the 1st November 2014 edition of the Lancet . . .

Poppers-Associated Retinal Toxicity

To the Editor: “Poppers” (slang for various forms of alkyl nitrite) are volatile nitric oxide donors that have been used for decades as recreational drugs. Both the popularity of and legal tolerance for poppers have led to the perception that these drugs are relatively innocuous.¹ Here, we describe four patients who were seen within a few months of one another and who had prolonged visual loss as a result of damage to foveal photoreceptors shortly after inhaling poppers.In January 2010, Patient 1, a 27-year-old woman, presented with an 11-day history of a reduction in bilateral vision and a “central . . .

The dangers of 'poppers': Using the sex drug just ONCE can cause irreversible damage to your eyes

A new generation of the sex drug 'poppers' can cause irreversible damage to the back of the eyes, scientists warn.
Just one use of the legal highs can trigger the deterioration of the fovea - the part of the retina responsible for the clearest vision.
Despite being designed to create feelings of euphoria, the main chemical ingredient can trigger side effects . . .

Poppers-Associated Retinal Toxicity

“Poppers” (slang for various forms of alkyl nitrite) are volatile nitric oxide donors that have been used for decades as recreational drugs. Both the popularity of and legal tolerance for poppers have led to the perception that these drugs are relatively innocuous.1 Here, we describe four patients who were seen within a few months of one another and who had prolonged visual loss as a result of damage to foveal photoreceptors shortly after inhaling poppers.In January 2010, Patient 1, a 27-year-old woman, presented with an 11-day history of a reduction in bilateral vision and a “central . . .

Protection against light-induced retinal degeneration by an inhibitor of NO synthase

The existence of nitric oxide synthase (NOS) in retinal rod outer segments and pigmented epithelial cells suggests that NO in excess could impair the interaction between these cells, resulting in photoreceptor degeneration. To test this hypothesis, NG-nitro-L-arginine methyl ester (L-NAME), an NOS inhibitor, was intraperitoneally injected daily into rats subjected to constant illumination for 7 days in order to destroy their photoreceptors. By measuring photoreceptor nuclear layer thicknesses, we found that L-NAME partially protects (by up to 35%) against the degeneration of photoreceptors and acts to maintain their organization. Thus NO may be involved in the process by which photoreceptor degeneration results from constant illumination of the retina. . . .

Poppers Maculopathy: Complete Restitution of Macular Changes in OCT after Drug Abstinence

“Poppers” is a slang term for a group of alkyl nitrites that are used as recreational drugs. Their inhalative intoxication leads to muscle relaxation, analgesia, and euphoria. Maculopathy is a rare but serious side-effect. Patients/Methods: Clinical, imaging, and electrophysiological findings of seven patients with maculopathy after consumption of poppers were presented. Results: All seven patients were male with a median age of 35 years (range 28–45 years), the median duration of periodical poppers use until the onset of symptoms was 9.8 years (one day to 25 years). Five of seven patients were HIV-positive, one patient was negative, and the HIV-status of one patient was unknown. Median average of visual acuity at presentation was 20/30 in each eye. In all patients, optical coherence tomography (OCT) showed pathognomonic alterations of the outer foveal retina. One patient showed an almost complete restitution of the maculopathy six months after cessation of drug use and following the oral intake of Lutein. Imaging alterations returned to normal and visual acuity recovered from 20/50 and 20/30 (right and left eye, respectively) to 20/20 on both eyes. Follow up of two other cases showed no relevant functional decline or improvement. . . .

Transient visual loss after amyl Isobutyl nitrite abuse

A 30-year-old man presented a sudden visual decrease following the use of Isobutyl nitrite (popper) while he was at a discotheque. His visual acuity (VA) was 20/50 in the right eye (RE) and 20/63 in the left eye (LE). Ophthalmoscopy revealed symmetric alteration of the foveal reflex with a small yellowish-white spot in the foveal area, much more evident in the RE. Fluorescein angiography and OCT were normal. Visual field showed a mild reduction of central differential light sensitivity. A progressive recovery was noted and at one month's follow-up VA was 20/25 in OU with very faint yellowish-white spots. . .

Poppers maculopathy

A 30-year-old white man with no ocular history presented to eye casualty in Sidcup in October, 2012, with bilateral central visual loss, following inhalation of poppers. On examination his visual acuity was 6/12 on the right and 6/18 in the left eye. Slit lamp biomicroscopy showed subtle macular changes in the form of yellow foveal spots. Spectral domain optical coherence tomography showed clear disruption of the foveal cone inner segment–outer segment layer. At follow-up 6 months later, the patient's visual acuity and examination findings remained unchanged, despite cessation of poppers use. . . .

Do not turn a blind eye to alkyl nitrite (poppers)!

Recreational users of poppers must be informed about the risk of developing poppers-associated maculopathy and the possible cumulative risk when taking poppers in combination with sildenafil. We suggest that it is an accumulative increase in cGMP which is harmful for the photoreceptor cells and may cause poppers-associated maculopathy
A possible association between the use of poppers and maculopathy with visual loss was first described in 2004. Poppers is the popular name for alkyl nitrite which is a short-acting, volatile drug used by inhalation. To better understand this possible association, we looked into the medical history and drug use of 10 patients with poppers-associated maculopathy.  . .

Poppers maculopathy or retinopathy?

The term ‘poppers' refers to exogenous volatile nitric oxide (NO) donors that have been widely abused for recreational purposes. Inhalation of poppers provides rapid-onset, short-acting euphoria and myorelaxation. Several reports described persistent visual loss after poppers consumption.
In all presented patients, functional and morphologic damage was limited to the fovea., We report two patients who not only developed a characteristic maculopathy following poppers consumption but also additionally showed a bilateral decline in full-field electroretinography (ERG). . . .

Health Canada issues warning over 'popper' found in adult video store

Health Canada has seized a new type of “popper” in Scarborough and warns that the ethyl chloride it contains could be deadly.
Poppers are products containing alkyl nitrites or ethyl chloride that are sometimes inhaled or ingested for recreational purposes despite being labelled for uses such as leather cleaners, room fresheners, cleaning solvents or liquid incense, Health Canada said.
The seizure was made at Homerama Adult Video at 2524 Eglinton Ave. E., according to a Health Canada advisory issued May 9.
Health Canada said the seized product, Premium Maximum Impact, is labelled for use as a cleaning solvent but is being sold as a “popper”.. . .

Advisory - Unauthorized sex enhancement products and poppers seized from stores in Edmonton, AB, and Maple Ridge, B.C.

OTTAWA, ON, March 28, 2022 /CNW/ - Health Canada is advising Canadians that the following products may pose serious health risks. For more information, including what Canadians should do, visit the online safety alert.
Health Canada maintains a list of unauthorized health products that may pose serious health risks so that Canadians can easily identify those they may have purchased and take appropriate action. Canadians are encouraged to check back regularly for updates.. . .